About Azathioprine Tablet

Azathioprine Tablet is a pharmaceutical product available in a pack of 10x10 tablets. Each tablet contains Azathioprine 50 mg as the active ingredient. Azathioprine is a medication that belongs to the class of immunosuppressants, which work by suppressing the immune system's activity. It is prescribed for various dermatological and autoimmune conditions. 

Glasierwellness is a leading manufacturer and wholesale supplier of Azathioprine Tablet in India

Compositions of Azathioprine Tablet

Azathioprine 50 mg 

Azathioprine is the active ingredient present in Glasiprin Tablet. It is an immunosuppressive medication that belongs to the class of drugs known as purine analogues. Azathioprine works by inhibiting the synthesis of DNA and RNA, which are essential components of the immune system. By suppressing the immune response, it helps to control the overactive immune system responsible for various autoimmune conditions. 

Azathioprine is converted in the body to its active metabolite, 6-mercaptopurine (6-MP). 6-MP acts as a purine antagonist and interferes with the production of purine nucleotides, which are vital for the proliferation of immune cells. This inhibits the division and maturation of lymphocytes, including T cells and B cells, reducing their numbers and dampening the immune response. 

It is important to note that azathioprine is a potent medication with potential side effects and requires careful monitoring during treatment. Regular blood tests may be necessary to assess the individual's blood cell count, liver function, and overall response to therapy. The dosage of azathioprine may need to be adjusted based on these parameters to ensure optimal efficacy and minimize the risk of adverse effects.

When to Use Azathioprine Tablet

Dermatomyositis:  Azathioprine Tablet is indicated for the treatment of dermatomyositis, a rare autoimmune disease characterized by muscle inflammation and skin involvement. It helps to reduce muscle inflammation, alleviate skin symptoms such as rash and redness, and improve overall disease control. 

Pemphigus Vulgaris: Pemphigus vulgaris is a chronic autoimmune blistering disorder that affects the skin and mucous membranes. Azathioprine Tablet is used as an adjunctive therapy to suppress the immune system and reduce the severity and frequency of blister formation, promoting healing and reducing the risk of complications. 

Pyoderma gangrenosum: Pyoderma gangrenosum is a rare, inflammatory skin condition characterized by the development of painful ulcers. Azathioprine Tablet is prescribed to control the immune response and reduce inflammation, promoting the healing of ulcers and preventing the spread of the disease. 

Cutaneous Vasculitis:  Azathioprine Tablet is indicated for the management of cutaneous vasculitis, a condition characterized by inflammation of the blood vessels in the skin. It helps to suppress the abnormal immune response, reduces vessel inflammation, and improves symptoms such as skin rash, pain, and swelling. 

Rheumatoid arthritis:  Azathioprine Tablet is used in the treatment of rheumatoid arthritis, a chronic inflammatory disorder that primarily affects the joints. It helps to suppress the immune response that leads to joint inflammation and damage, providing relief from pain, reducing joint swelling, and improving overall joint function. 

Systemic lupus erythematosus:  Azathioprine Tablet is prescribed for systemic lupus erythematosus (SLE), a chronic autoimmune disease that can affect multiple organs and tissues. It helps to suppress the immune system's hyperactivity, reducing inflammation, managing organ involvement, and improving overall disease control. 

Severe Atopic Eczema:  Severe Atopic eczema, also known as  Severe atopic dermatitis, is a  chronic inflammatory skin condition characterized by itchy, red, and dry skin. Azathioprine Tablet is used as part of a comprehensive treatment plan to manage severe atopic eczema by reducing inflammation, relieving itching, and improving skin barrier function. 

Chronic actinic dermatitis: Chronic actinic dermatitis is a type of eczematous reaction that occurs as a result of exposure to sunlight. Azathioprine Tablet is prescribed to reduce the immune system's response to ultraviolet radiation, minimizing skin inflammation, and alleviating symptoms such as redness, itching, and skin lesions. 

Autoimmune diseases:  Azathioprine Tablet is indicated for the management of various autoimmune diseases where the immune system mistakenly attacks the body's own tissues. It helps to suppress the abnormal immune response, reducing inflammation, and minimizing tissue damage in conditions such as autoimmune hepatitis, autoimmune thyroiditis, and autoimmune cytopenias.

Benefits of Azathioprine Tablet

Effective management of dermatomyositis:  Azathioprine Tablet provides effective management of dermatomyositis by suppressing the abnormal immune response responsible for muscle inflammation and skin involvement. It helps reduce muscle inflammation, alleviate skin symptoms, and improve overall disease control. 

Control of pemphigus vulgaris:  Azathioprine Tablet plays a vital role in controlling pemphigus vulgaris, a chronic autoimmune blistering disorder. By suppressing the immune system, it helps reduce the severity and frequency of blister formation, promoting healing and reducing the risk of complications. 

Healing of pyoderma gangrenosum:  Azathioprine Tablet aids in the healing process of pyoderma gangrenosum, a rare inflammatory skin condition characterized by the development of painful ulcers. It suppresses the abnormal immune response, reducing inflammation and promoting the healing of ulcers. 

Reduction of cutaneous vasculitis symptoms:  Azathioprine Tablet effectively reduces the symptoms of cutaneous vasculitis, such as skin rash, pain, and swelling. By suppressing the immune response and reducing vessel inflammation, it improves the overall management of the condition. 

Relief from rheumatoid arthritis symptoms:  Azathioprine Tablet provides relief from the symptoms of rheumatoid arthritis by suppressing the immune response that leads to joint inflammation and damage. It helps reduce pain, joint swelling, and stiffness, improving overall joint function. 

Improved control of systemic lupus erythematosus:  Azathioprine Tablet plays a crucial role in the management of systemic lupus erythematosus (SLE), a chronic autoimmune disease. Suppressing the immune system's hyperactivity helps reduce inflammation, manage organ involvement, and improve overall disease control. 

Alleviation of  Severe atopic eczema symptoms:  Azathioprine Tablet is effective in alleviating the symptoms of severe atopic eczema, such as itching, redness, and dry skin. It helps reduce inflammation, relieve itching, and improve skin barrier function, leading to improved skin health. 

Management of chronic actinic dermatitis:  Azathioprine Tablet helps manage chronic actinic dermatitis, a condition caused by exposure to sunlight. By reducing the immune system's response to ultraviolet radiation, it minimizes skin inflammation, relieves symptoms such as redness and itching, and helps protect the skin from further damage. 

Control of autoimmune diseases:  Azathioprine Tablet is beneficial in managing various autoimmune diseases, where the immune system mistakenly attacks the body's own tissues. Suppressing the abnormal immune response, it helps reduce inflammation and minimize tissue damage in conditions such as autoimmune hepatitis, autoimmune thyroiditis, and autoimmune cytopenias. 

Enhanced quality of life: The overall benefits of Azathioprine Tablet in managing autoimmune and dermatological conditions lead to an improved quality of life for individuals. By reducing symptoms, controlling inflammation, and preventing complications, it allows individuals to engage in daily activities more comfortably and confidently. 

Long-term disease control:  Azathioprine Tablet helps in achieving long-term disease control in chronic autoimmune and dermatological conditions. By suppressing the immune system, it helps maintain remission, reduce flare-ups, and prevent disease progression, allowing individuals to have better control over their health. 

Reduced dependency on other medications:  Azathioprine Tablet's effectiveness in managing autoimmune and dermatological conditions may lead to a reduced dependency on other medications. It can potentially lower the need for high-dose corticosteroids or other immunosuppressants, minimizing their associated side effects and improving overall treatment outcomes. Prevention of complications: By effectively managing autoimmune and dermatological conditions, Azathioprine Tablet helps prevent complications associated with these diseases.  

Enhanced skin health:  Azathioprine Tablet contributes to enhanced skin health by reducing inflammation and promoting healing. It helps to alleviate skin conditions associated with autoimmune diseases, allowing the skin to regain its natural balance and improve its overall appearance and texture. 

Improved joint function: For individuals with rheumatoid arthritis, Azathioprine Tablet can improve joint function by reducing inflammation and preventing further damage to the joints. This can lead to increased mobility, reduced joint stiffness, and enhanced overall joint function. 

Minimized disease activity:  Azathioprine Tablet helps in minimizing disease activity in autoimmune conditions such as systemic lupus erythematosus. Suppressing the immune system's overactivity can reduce the frequency and severity of disease flares, allowing individuals to experience longer periods of remission and stability. 

Reduced skin sensitivity: In conditions like chronic actinic dermatitis, Azathioprine Tablet can help reduce skin sensitivity to sunlight. By suppressing the immune response to ultraviolet radiation, it minimizes the skin's reactivity and discomfort upon sun exposure, enabling individuals to enjoy outdoor activities with reduced risk of flare-ups. 

Potential remission induction: In some cases, Azathioprine Tablet may play a role in inducing remission in autoimmune conditions. By modulating the immune response, it can help regulate the abnormal immune activity and achieve a state of remission where the disease becomes inactive or less active, providing relief from symptoms and improving overall well-being. 

Decreased reliance on systemic steroids: For individuals with autoimmune and dermatological conditions, Azathioprine Tablet may reduce the need for long-term systemic steroid use. By providing effective immunosuppression, it can lower the dosage and duration of steroid therapy, minimizing the associated side effects and long-term complications. 

Management of systemic manifestations: Autoimmune diseases often involve systemic manifestations beyond the skin. Azathioprine Tablet can help manage these systemic symptoms by reducing overall inflammation and immune dysregulation, providing relief from conditions such as fever, fatigue, and malaise. 

Tailored treatment approach:  Azathioprine Tablet allows for a more tailored treatment approach in autoimmune and dermatological conditions. The dosage can be adjusted according to individual needs, ensuring optimal therapeutic outcomes while considering factors such as disease severity, response to treatment, and individual tolerance. 

Potential reduction in hospitalizations: Effective management of autoimmune and dermatological conditions with Azathioprine Tablet may lead to a reduction in hospitalizations. By controlling disease activity, minimizing complications, and promoting disease stability, individuals may experience fewer exacerbations requiring hospital-based care. 

Psychological well-being: The benefits of Azathioprine Tablet extend beyond physical symptoms, positively impacting psychological well-being. By controlling disease activity, reducing symptoms, and improving overall health, it can alleviate stress, anxiety, and depression associated with chronic autoimmune and dermatological conditions. 

Improved treatment adherence:  Azathioprine Tablet's effectiveness in managing autoimmune and dermatological conditions may enhance treatment adherence. By providing noticeable relief from symptoms and improving quality of life, individuals are more likely to adhere to their treatment regimens, leading to better long-term outcomes. 

Potential prevention of long-term complications: Through its immunosuppressive effects, Azathioprine Tablet may help prevent long-term complications associated with autoimmune and dermatological conditions. By controlling inflammation and immune dysregulation, it can reduce the risk of irreversible organ damage, scarring, and other long-term sequelae. 

The individualized approach to care:  Azathioprine Tablet allows for an individualized approach to care, where the treatment plan is tailored to the specific needs of each patient. Healthcare professionals can assess the individual's response to therapy, monitor side effects, and make necessary adjustments to dosage or combination treatments for optimal results. 

Collaborative care management:  Azathioprine Tablet promotes collaborative care management, involving healthcare professionals from various specialties. In complex autoimmune and dermatological conditions, a multidisciplinary team approach ensures comprehensive and holistic care, addressing both the systemic and dermatological aspects of the disease. 

Potential reduction in healthcare costs: Effective management of autoimmune and dermatological conditions with Azathioprine Tablet may result in a potential reduction in healthcare costs. By controlling disease activity, minimizing complications, and reducing the need for hospitalizations or high-dose medications, can lead to cost savings for both patients and healthcare systems. 

Long-term disease stability:  Azathioprine Tablet's benefits extend to promoting long-term disease stability in autoimmune and dermatological conditions. By modulating the immune response and suppressing disease activity, it can contribute to prolonged periods of remission, reducing the frequency and intensity of disease flares. 

Enhanced overall well-being: Ultimately, the benefits of Azathioprine Tablet contribute to enhanced overall well-being for individuals with autoimmune and dermatological conditions. By managing symptoms, preventing complications, and promoting disease control, it allows individuals to lead a more fulfilling and active life, improving their physical, emotional, and social well-being.

How to Use Azathioprine Tablet

• Consult your healthcare provider before starting Azathioprine Tablet and follow their prescribed dosage and instructions.
• Take Azathioprine Tablet orally with or without food, as directed by your healthcare provider.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet unless instructed otherwise.
• Take Azathioprine Tablet at the same time(s) each day to maintain a consistent level of medication in your body.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
• Continue taking Azathioprine Tablet for the duration prescribed by your healthcare provider, even if you start feeling better. Stopping the medication abruptly or without medical guidance may result in a recurrence of symptoms or disease flare-ups.

How to Storage Azathioprine Tablet

• Store Azathioprine Tablet in its original packaging or container to protect it from moisture and light.
• Keep the medication out of reach of children and pets.
• Store Azathioprine Tablet at room temperature, away from direct sunlight and excessive heat.
• Do not store the medication in the bathroom or any other area with high humidity or temperature fluctuations.
• If you have any unused or expired Azathioprine Tablet, dispose of them properly according to local guidelines or consult your pharmacist for guidance.

Caution:

• Azathioprine Tablet is a prescription medication and should only be taken under the supervision of a healthcare professional.
• Inform your healthcare provider about any medical conditions you have, including allergies, liver or kidney problems, or a history of blood disorders.
• Inform your healthcare provider about all the medications, supplements, or herbal products you are currently taking, as they may interact with Azathioprine Tablet.
• Follow your healthcare provider's instructions regarding regular monitoring of your blood cell counts, liver function, and other relevant laboratory tests to ensure the safe and effective use of the Azathioprine Tablet.
• If you experience any severe or persistent side effects, such as signs of infection, unusual bleeding or bruising, severe nausea or vomiting, or allergic reactions, seek immediate medical attention.
• Avoid excessive exposure to sunlight or ultraviolet (UV) light while taking Azathioprine Tablet, as it may increase the risk of sunburn or photosensitivity reactions. Use appropriate sun protection measures, such as wearing protective clothing and using sunscreen.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using the Azathioprine Tablet with your healthcare provider before starting the medication.
• Do not share Azathioprine Tablet with others, as it is prescribed specifically for your condition and may not be suitable for their medical needs.
• Follow any additional precautions or recommendations provided by your healthcare provider for the safe and effective use of the Azathioprine Tablet.

Disclaimer:

The following disclaimer provides important information about the use of Azathioprine Tablet. Please read this disclaimer carefully before using the medication: 

Medical Advice: The information provided about Azathioprine Tablet is for informational purposes only and should not be considered medical advice. It is not intended to replace the advice, diagnosis, or treatment provided by qualified healthcare professionals. Always consult your healthcare provider or pharmacist for personalized medical advice and guidance regarding your specific condition. 

Individual Variations: The benefits, indications, and outcomes of Azathioprine Tablet may vary among individuals. The medication's effectiveness and tolerability can depend on factors such as the severity of the condition, underlying health conditions, other medications being taken, and individual response. Therefore, results may differ from person to person. 

Healthcare Provider's Guidance:  Azathioprine Tablet should only be used under the guidance and supervision of a qualified healthcare professional. Your healthcare provider will assess your medical history, conduct appropriate tests, and determine the appropriate dosage and duration of treatment based on your specific condition. Always follow their instructions and do not modify the dosage or treatment plan without consulting them. 

Adverse Effects and Allergies: Like any medication, Azathioprine Tablet may cause side effects or allergic reactions in some individuals. Common side effects may include gastrointestinal discomfort, nausea, vomiting, headaches, and changes in blood cell counts. If you experience any severe or persistent side effects, discontinue use and seek immediate medical attention. Inform your healthcare provider about any known allergies or sensitivities before taking Azathioprine Tablet. 

Precautions: Certain precautions should be observed while using Azathioprine Tablet. This includes informing your healthcare provider about all your current medications, herbal supplements, or over-the-counter drugs to avoid potential drug interactions. Additionally, caution should be exercised in special populations such as pregnant or breastfeeding individuals, children, and the elderly. Always follow your healthcare provider's instructions and guidelines. 

Risks and Benefits: While Azathioprine Tablet can provide significant benefits in the management of specific conditions, it is important to weigh the potential risks against the potential benefits. Your healthcare provider will assess the benefits and risks associated with Azathioprine Tablet based on your individual situation and health status. 

Changes in Information: The information provided about Azathioprine Tablet is based on the available knowledge and research up to the date of this disclaimer. New information or research findings may emerge that could change the understanding or recommendations regarding the use of the medication. It is important to stay updated and consult trusted sources for the most current information. 

Legal Disclaimer: The manufacturer, distributor, and all parties involved in the creation, distribution, and provision of Azathioprine Tablet and its related information do not assume any liability for any direct or indirect damages, losses, or consequences resulting from the use of the medication or reliance on the information provided.