About of Tofacitinib Tablet

Tofacitinib Tablet is a medication available in tablet form that contains the active ingredient Tofacitinib 5 mg. Each pack of Tofacitinib Tablet comes with 10 strips, and each strip contains 10 tablets, resulting in a total of 100 tablets per pack. The tablets are designed to be easily swallowed and are intended for oral administration. 

Tofacitinib Tablet is a prescription medication used for the treatment of various conditions, including Alopecia Areata, Rheumatoid Arthritis, Psoriatic Arthritis, Ulcerative Colitis & Vitiligo. It works by reducing inflammation and modulating the immune response to alleviate symptoms associated with these conditions. 

Glasierwellness is a leading manufacturer and wholesale supplier of Tofacitinib Tablet in India

Composition of Tofacitinib Tablet

TOFACITINIB 5 MG 

Tofacitinib is a potent Janus kinase (JAK) inhibitor that exerts its therapeutic effects by selectively targeting and inhibiting specific enzymes involved in the inflammatory process. It is a small molecule that inhibits JAK1 and JAK3 enzymes, which are crucial components of signalling pathways involved in immune responses and inflammatory processes. 

When administered orally, Tofacitinib is rapidly absorbed into the bloodstream, reaching peak plasma concentrations within a few hours. It has a high bioavailability, allowing for effective systemic distribution throughout the body. 

In Rheumatoid Arthritis, Tofacitinib helps reduce joint inflammation and destruction by suppressing the production of inflammatory mediators and inhibiting the activation of immune cells involved in the pathogenesis of the disease. By modulating the immune response, Tofacitinib helps alleviate the signs and symptoms of Rheumatoid Arthritis, including joint pain, swelling, stiffness, and functional impairment. 

In Psoriatic Arthritis, Tofacitinib inhibits JAK signalling pathways that contribute to joint inflammation and structural damage. By targeting the underlying immune dysregulation and inflammatory processes, it helps manage the symptoms associated with Psoriatic Arthritis, such as joint pain, swelling, enthesitis, dactylitis, and skin manifestations. 

In Ulcerative Colitis, Tofacitinib acts on the inflamed mucosa of the colon by suppressing the production of pro-inflammatory cytokines, which contribute to the chronic inflammation and tissue damage seen in the disease. It helps induce and maintain remission by modulating the immune response and reducing the severity of symptoms, including abdominal pain, diarrhoea, rectal bleeding, and urgency. 

Regarding Alopecia Areata, Tofacitinib has shown promising results in promoting hair regrowth in individuals with moderate to severe forms of the condition. It is believed to work by interrupting the immune-mediated attack on hair follicles and promoting the restoration of hair growth.

Indications of Tofacitinib Tablet

Alopecia Areata: Tofacitinib Tablet is indicated for the treatment of Alopecia Areata, a condition characterized by sudden hair loss that can occur on the scalp or other areas of the body. It is also used for the following indications: 

Rheumatoid Arthritis:  Tofacitinib Tablet is used to manage the signs and symptoms of rheumatoid arthritis, including joint pain, swelling, and stiffness. 

Psoriatic Arthritis: It is indicated for the treatment of psoriatic arthritis, a form of arthritis that affects individuals with psoriasis, causing joint pain and inflammation. 

Ulcerative Colitis:  Tofacitinib Tablet is prescribed for the management of ulcerative colitis, a type of inflammatory bowel disease that leads to inflammation and ulcers in the colon and rectum. 

Vitiligo: Tofacitinib Tablet is also indicated for the treatment of vitiligo. Vitiligo is a long-term skin condition characterized by the loss of skin color in patches, resulting in depigmented white patches on various parts of the body. Tofacitinib Tablet may help to manage the progression of vitiligo and promote repigmentation of the affected areas.

Benefits of Tofacitinib Tablet

• Tofacitinib Tablet effectively promotes hair regrowth and reduces hair loss in individuals with Alopecia Areata.
• It helps manage the symptoms of rheumatoid arthritis, such as joint pain, swelling, and morning stiffness.
• Tofacitinib Tablet can alleviate joint pain and inflammation associated with psoriatic arthritis.
• It aids in reducing the inflammation and other symptoms of ulcerative colitis, such as abdominal pain and diarrhoea.
• The medication improves the quality of life for individuals suffering from Alopecia Areata by restoring hair growth.
• It reduces the progression of joint damage and improves physical function in rheumatoid arthritis patients.
• Tofacitinib Tablet helps control the symptoms of psoriatic arthritis, including skin rash and nail changes.
• It assists in achieving and maintaining remission in ulcerative colitis patients.
• The medication has shown promising results in promoting hair regrowth in individuals with extensive Alopecia Areata.
• Tofacitinib Tablet helps manage the systemic symptoms associated with rheumatoid arthritis, such as fatigue and fever.
• It can be used as a long-term treatment option for psoriatic arthritis to control disease activity and prevent joint damage.
• Tofacitinib Tablet reduces the need for corticosteroids in ulcerative colitis patients.
• The medication improves scalp coverage and hair density in individuals with Alopecia Areata.
• It helps reduce morning stiffness and improves joint mobility in rheumatoid arthritis.
• Tofacitinib Tablet assists in the prevention of structural damage to joints in psoriatic arthritis patients.
• It aids in achieving and maintaining mucosal healing in ulcerative colitis.
• The medication improves self-esteem and psychological well-being in individuals with Alopecia Areata.
• It helps manage extra-articular manifestations of rheumatoid arthritis, such as vasculitis and lung disease.
• Tofacitinib Tablet can relieve pain and swelling in enthesitis (inflammation where tendons or ligaments attach to bones) associated with psoriatic arthritis.
• The medication helps decrease the frequency and severity of flare-ups in ulcerative colitis, leading to better disease control.
• It improves physical function and enhances the overall quality of life for individuals with rheumatoid arthritis.
• The medication reduces skin inflammation, scaling, and redness associated with psoriatic arthritis.
• Tofacitinib Tablet helps achieve and maintain remission in ulcerative colitis, minimizing the need for surgery.
• It provides long-term management and control of symptoms in Alopecia Areata, preventing future hair loss.
• The medication helps reduce joint tenderness and swelling, allowing for improved mobility in rheumatoid arthritis.
• It can be used as a monotherapy or in combination with other treatments for psoriatic arthritis to achieve optimal disease control.
• Tofacitinib Tablet reduces the frequency of ulcerative colitis flares, leading to longer periods of symptom-free remission.

Directions for Use of Tofacitinib Tablet

Follow the instructions provided by your healthcare provider regarding the dosage and duration of treatment with the Tofacitinib Tablet. It is typically taken orally with or without food. Swallow the tablet whole with a glass of water and do not crush, chew, or break it unless advised otherwise.

Storage:

Store TofacitinibTablet in a cool, dry place away from direct sunlight and out of reach of children. Follow the storage instructions mentioned on the packaging. Do not use the medication beyond its expiration date.

Caution:

Tofacitinib Tablet should be used under the guidance and supervision of a healthcare professional. Inform your doctor about any existing medical conditions, ongoing treatments, or allergies before initiating treatment with this medication. Adhere to the prescribed dosage and do not exceed the recommended duration of use.

Disclaimer:

The information provided here is for informational purposes only and does not constitute medical advice. This disclaimer applies to the product Tofacitinib Tablet and its associated information. 

Consultation with Healthcare Professionals: The use of the Tofacitinib Tablet should be discussed and determined in consultation with a qualified healthcare professional. They will assess your medical condition, consider potential risks and benefits, and provide personalized recommendations based on your specific needs. 

Individual Responses: The effects of the Tofacitinib Tablet may vary from person to person. Different individuals may respond differently to the medication due to variations in their medical history, underlying conditions, and other factors. Results and outcomes cannot be guaranteed. 

Professional Guidance: The information provided in the product description, including indications and benefits, should not replace the advice or expertise of a healthcare professional. Always rely on the guidance and recommendations of a qualified healthcare provider for the appropriate use of the Tofacitinib Tablet. 

Adverse Reactions:  Tofacitinib Tablet, like any medication, may have potential side effects or adverse reactions. These can range from mild to severe and may vary among individuals. It is essential to be aware of the possible adverse effects and report any unusual symptoms promptly to a healthcare professional. 

Contraindications: Certain medical conditions, medications, or treatments may contraindicate the use of the Tofacitinib Tablet. It is crucial to disclose your complete medical history, including current medications, to your healthcare provider to determine if Tofacitinib Tablet is safe and suitable for you. 

Allergic Reactions: Individuals with known allergies or hypersensitivity to Tofacitinib or any other component of the Tofacitinib Tablet should avoid its use. If you experience signs of an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing, seek immediate medical attention. 

Compliance and Dosage: It is important to strictly adhere to the prescribed dosage and follow the instructions provided by your healthcare professional or as indicated on the product packaging. Deviating from the recommended dosage or duration of treatment may affect the safety and efficacy of the Tofacitinib Tablet. 

Monitoring and Follow-up: Regular monitoring and follow-up appointments with your healthcare provider are essential to evaluate the response to treatment, monitor any potential side effects, and make any necessary adjustments to the therapy. 

Product Authenticity: Ensure that you obtain Tofacitinib Tablet from reliable and reputable sources to ensure product authenticity, quality, and safety. 

Legal Considerations: The manufacturer, distributor, and any associated parties are not liable for any direct or indirect damages or consequences arising from the use, misuse, or interpretation of the information provided or the use of the Tofacitinib Tablet. 

Always consult a qualified healthcare professional for advice, diagnosis, and treatment of medical conditions.